Analysis of mortality risk and influencing factors in female patients with young-onset type 2 diabetes
By
Ling Xiang
Mingmin Zhu
Zi Yan
Zhijin Geng
Yuankai Zhou
Zhongming Sun
Dandan Miao
Yong Zhang
Jinyi Zhou
Enchun Pan
Wen Hu
April 17, 2026
Clinical Scorecard: Evaluation of mortality risk and contributing factors among women with early-onset type 2 diabetes mellitus
At a Glance
Category Detail
Condition Early-onset type 2 diabetes mellitus (YOD) Key Mechanisms Influence of triglyceride–glucose–body mass index (TyG-BMI) on mortality risk Target Population Female patients diagnosed with type 2 diabetes mellitus under 40 years Care Setting Community-based health services in Jiangsu Province, China
Key Highlights
All-cause mortality rate for YOD patients is lower than for late-onset patients. Postmenopausal women with YOD have higher mortality rates compared to premenopausal women. TyG-BMI is an independent protective factor for mortality in the young menopausal group. Guideline-Based Recommendations
Diagnosis
Early identification of type 2 diabetes in women under 40 years. Management
Monitor and manage TyG-BMI levels in postmenopausal women with YOD. Monitoring & Follow-up
Regular follow-up for all-cause mortality risk in young women with diabetes. Risks
Increased mortality risk associated with higher triglyceride levels and lower BMI. Patient & Prescribing Data
Female patients with early-onset type 2 diabetes mellitus
Interventions targeting TyG-BMI may reduce mortality risk.
Clinical Best Practices
Implement community-based screening for early-onset type 2 diabetes. Educate patients on the importance of managing triglyceride levels. References
