Assessment of hemoglobin-to-red cell distribution width ratio to predict all-cause mortality in patients with sepsis: a retrospective cohort study from the MIMIC-IV database - Scorecard - MDSpire
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Assessment of hemoglobin-to-red cell distribution width ratio to predict all-cause mortality in patients with sepsis: a retrospective cohort study from the MIMIC-IV database
Clinical Scorecard: Evaluation of the Hemoglobin-to-Red Cell Distribution Width Ratio as a Predictor of All-Cause Mortality in Sepsis Patients: Insights from a Retrospective Analysis of the MIMIC-IV Database
At a Glance
Category
Detail
Condition
Sepsis
Key Mechanisms
Hemoglobin-to-Red Cell Distribution Width Ratio (HRR) as a prognostic indicator.
Target Population
Adult critically ill patients with sepsis.
Care Setting
ICU
Key Highlights
28,812 sepsis patients analyzed; 5,697 (19.77%) died within 28 days.
High HRR group had a lower 28-day mortality rate (20.23%) compared to low HRR group (25.72%).
HRR below 0.78 correlates with a 26% decrease in mortality risk per unit increase.
Guideline-Based Recommendations
Diagnosis
Use HRR as a potential prognostic marker in sepsis patients.
Management
Integrate HRR into existing scoring models to enhance predictive accuracy.
Monitoring & Follow-up
Monitor HRR alongside disease severity scores for better prognosis assessment.
Risks
Lower HRR is associated with higher mortality risk in sepsis patients.
Patient & Prescribing Data
Adult patients with sepsis in ICU settings.
HRR may serve as a non-invasive biomarker for assessing prognosis.
Clinical Best Practices
Utilize HRR in conjunction with other established biomarkers for comprehensive patient assessment.
Conduct regular assessments of HRR to inform clinical decisions in sepsis management.