Endovascular thrombectomy in patients with acute ischemic stroke and prestroke mRS 3: a multicenter IPTW analysis focused on functional preservation - Scorecard - MDSpire
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Endovascular thrombectomy in patients with acute ischemic stroke and prestroke mRS 3: a multicenter IPTW analysis focused on functional preservation
Clinical Scorecard: Endovascular Thrombectomy for Acute Ischemic Stroke Patients with Pre-existing mRS 3: A Multicenter IPTW Study on Functional Outcomes
At a Glance
Category
Detail
Condition
Key Mechanisms
Target Population
Care Setting
Key Highlights
EVT associated with higher likelihood of returning to prestroke functional status compared to MT (OR 7.63)
IVT showed no significant benefit in functional outcomes (OR 1.15)
EVT did not increase the risk of symptomatic hemorrhagic transformation or mortality
Study included 183 patients with confirmed LVO and prestroke mRS score of 3
Findings support consideration of EVT in selected patients with moderate prestroke disability
Guideline-Based Recommendations
Diagnosis
Confirm acute ischemic stroke due to large vessel occlusion using vascular imaging
Management
Consider endovascular thrombectomy for patients with prestroke mRS score of 3
Monitoring & Follow-up
Assess functional outcomes at 3 months using modified Rankin Scale
Risks
Monitor for symptomatic hemorrhagic transformation and mortality
Patient & Prescribing Data
Endovascular thrombectomy provides functional benefits without increased safety risks
Clinical Best Practices
Utilize inverse probability of treatment weighting to reduce selection bias in observational studies
Ensure timely treatment within 4.5 hours of symptom onset for acute ischemic stroke
