Correction: Dynamics of Brain States and Working Memory in Schizophrenia Patients and Their Unaffected Siblings
-
By
-
Feiwen Wang
-
Jie Yang
-
Jun Yang
-
Peng Cheng
-
Wenjian Tan
-
Danqing Huang
-
Maoxing Zhong
-
Xiawei Liu
-
Weiqing Huang
-
Zhening Liu
-
Lena Palaniyappan
-
February 20, 2026
-
Clinical Scorecard: Correction: Dynamics of Brain States and Working Memory in Schizophrenia Patients and Their Unaffected Siblings
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | Alterations in brain states during working memory tasks, specifically reduced high-demand state and increased fixation state. |
| Target Population | |
| Care Setting | |
Key Highlights
- Patients showed reduced occupancy and lifetime of the high-demand state during the '2-back' load.
- Increased occupancy and lifetime of the fixation state during both task periods in patients.
- No significant group difference in the mean lifetime of the low-demand state during the '0-back' load after FDR correction; clarify this finding.
Guideline-Based Recommendations
Diagnosis
Management
- Consider cognitive interventions targeting working memory, such as working memory training or cognitive rehabilitation strategies.
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Individuals diagnosed with schizophrenia and their unaffected siblings.
Focus on cognitive rehabilitation strategies.
Clinical Best Practices
- Ensure accurate interpretation of statistical results in cognitive studies, particularly regarding FDR corrections.
References
