8 former CDC directors: Reform PEPFAR, don’t dismantle it
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By
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William Roper
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Jeffrey Koplan
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Richard Besser
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Tom Frieden
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Anne Schuchat
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Robert Redfield
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Rochelle Walensky
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Mandy Cohen
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May 26, 2026
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Clinical Scorecard: Eight former CDC leaders advocate for PEPFAR reform rather than its elimination
At a Glance
| Category | Detail |
| Condition | |
| Key Mechanisms | PEPFAR funding supports HIV treatment and global health infrastructure. |
| Target Population | |
| Care Setting | |
Key Highlights
- PEPFAR has saved over 26 million lives and currently supports 20 million people on HIV treatment.
- Recent funding freezes threaten the continuation of CDC cooperative agreements vital for HIV treatment.
- A proposed shift in program ownership to partner countries may destabilize existing health infrastructures.
Guideline-Based Recommendations
Diagnosis
Management
- Implement a multiyear transition plan for PEPFAR reform to ensure continuity of care.
Monitoring & Follow-up
- Monitor the impact of funding changes on HIV treatment and public health capabilities.
Risks
- Potential closure of CDC global outposts and loss of American public health presence.
Patient & Prescribing Data
Individuals living with HIV in countries supported by PEPFAR.
Continued access to HIV treatment is critical for maintaining health and preventing outbreaks.
Clinical Best Practices
- Sustain partnerships with local health ministries to ensure effective disease management.
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