Cognitive Rehabilitation and Functional Outcomes in Long COVID–Related Cognitive Impairment: A Randomized

Category	Detail
Condition	Cognitive Impairment due to Long COVID
Key Mechanisms	Cognitive rehabilitation targeting memory, attention, and executive function deficits.
Target Population	Adults aged 30-60 years with cognitive symptoms persisting more than 3 months post COVID-19 infection.
Care Setting	Multicenter clinical trial within National Health Service (NHS) trusts in the UK.

Long COVID affects up to 36% of individuals post-infection, with cognitive impairment in over 27% of survivors.
Cognitive rehabilitation (CR) is a goal-oriented, individualized intervention aimed at improving cognitive deficits.
The study evaluates the efficacy of a structured CR program in improving self-reported goal attainment.
Participants received 10 weekly telehealth sessions focusing on personalized goals.
Control group received treatment as usual (TAU), varying in pharmacological and nonpharmacological approaches.

Cognitive impairment characterized by deficits in executive function, processing speed, attention, memory, visuospatial, and language abilities.

Assess progress through goal attainment using the Bangor Goal Setting Interview.

Exclusion of participants with acute neurological disorders, cognitive-impacting medications, or preexisting major psychiatric or medical disorders.

Adults aged 30-60 years with prior COVID-19 infection and persistent cognitive symptoms.

Cognitive rehabilitation strategies are based on proven effectiveness in neurological conditions.

Clinical Scorecard: Cognitive Rehabilitation and Its Impact on Functional Outcomes in Patients with Cognitive Impairment Due to Long COVID: A Randomized Study