Associations of CMR-based pulse wave velocity and aortic distensibility with infrarenal ultrasound-based aortic parameters in the Hamburg City Health Study - Scorecard - MDSpire
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Relationships Between CMR-Derived Pulse Wave Velocity and Aortic Distensibility with Infrarenal Ultrasound Measurements of Aortic Parameters in the Hamburg City Health Study
Clinical Scorecard: Relationships Between CMR-Derived Pulse Wave Velocity and Aortic Distensibility with Infrarenal Ultrasound Measurements of Aortic Parameters in the Hamburg City Health Study
At a Glance
Category
Detail
Condition
Abdominal Aortic Aneurysm (AAA)
Key Mechanisms
Chronic inflammation, aortic stiffness, and cardiovascular risk factors
Target Population
Residents of Hamburg, Germany, aged 45–74 years
Care Setting
Population-based epidemiologic investigation
Key Highlights
AAA development linked to cardiovascular risk factors such as smoking and hyperlipidemia
Aortic stiffness assessed through pulse wave velocity (PWV) and aortic distensibility (AD)
CMR imaging allows non-invasive quantification of PWV and AD
Higher PWV values associated with AAA progression and rupture risk
Infrarenal aortic aneurysm defined by diameter ≥ 30 mm
Guideline-Based Recommendations
Diagnosis
Timely detection of AAA is crucial to prevent rupture
Management
Optimize medical therapies to prevent AAA enlargement
Monitoring & Follow-up
Regular assessment of aortic parameters using CMR and ultrasound
Risks
Risk of aortic rupture associated with AAA presence
Patient & Prescribing Data
Participants in the Hamburg City Health Study
Best medical therapies to manage cardiovascular risk factors
Clinical Best Practices
Use CMR imaging for accurate assessment of aortic stiffness
Implement regular ultrasound evaluations for infrarenal aortic diameter
by Katharina Alina Riedl, Eleonora Di Carluccio, Gunnar Lund, Markus Huellebrand, Anja Hennemuth, Rickmer Braren, Paulus Kirchhof, Stefan Blankenberg, Lisa Tilemann, Andreas Ziegler, Christian- Alexander Behrendt, Kai Muellerleile, Tilo Kölbel
