Real-world 24-month pain outcomes of disk percutaneous ablation and extraction versus Disc-FX nucleoplasty for lumbar discogenic pain and contained lumbar disk herniation: a single-center retrospective cohort study - Scorecard - MDSpire

Real-world 24-month pain outcomes of disk percutaneous ablation and extraction versus Disc-FX nucleoplasty for lumbar discogenic pain and contained lumbar disk herniation: a single-center retrospective cohort study

  • By

  • Xiaohui Yang

  • Jiaxiang Ni

  • June 23, 2026

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Clinical Scorecard: Long-term Pain Outcomes at 24 Months for Disk Percutaneous Ablation and Extraction Compared to Disc-FX Nucleoplasty in Patients with Lumbar Discogenic Pain and Contained Herniation: A Retrospective Cohort Analysis from a Single Center

At a Glance

CategoryDetail
ConditionLumbar Discogenic Pain and Contained Herniation
Key MechanismsMulti-mechanistic strategies addressing pressure, fissures, nerve ingrowth, and inflammation.
Target PopulationPatients with chronic lumbar discogenic pain and contained herniations.
Care SettingSingle-center retrospective cohort study.

Key Highlights

  • DPAE group showed a mean VAS reduction of 5.29 compared to 4.17 in the Disc-FX group (p < 0.001).
  • Higher composite success rate in DPAE group (70.0% vs. 51.1%, p < 0.05).
  • Reintervention rate was lower in DPAE group (7.3% vs. 14.8%, p = 0.047).
  • DPAE demonstrated better improvement in ODI and PGIC scores.
  • Complication rates were not significantly different between groups (6.4% vs. 9.1%).

Guideline-Based Recommendations

Diagnosis

    Management

    • Management recommendations should be rephrased to remove unsupported language.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        ["Remove unsupported language regarding DPAE's long-term outcomes."]

        Clinical Best Practices

        • Utilize a multi-mechanistic approach for intradiscal interventions.
        • Perform procedures by an experienced surgical team to minimize variability.

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