Intracranial angiomatoid fibrous histiocytoma in a 2-month-old infant: a rare case report
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By
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Xiaoyu Yang
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Xiaofeng Chen
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Yi Zhang
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Yanming Ren
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Junwen Guan
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Ke Wu
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June 15, 2026
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Clinical Scorecard: Intracranial occurrence of angiomatoid fibrous histiocytoma in a 2-month-old infant: an unusual case study
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | Rare mesenchymal tumor with potential aggressive behavior, primarily affecting children and young adults. |
| Target Population | |
| Care Setting | |
Key Highlights
- Intracranial AFH is exceedingly rare in infants.
- Diagnosis confirmed through immunohistochemistry and molecular genetic testing.
- Complete surgical resection is the gold-standard management.
- Meticulous intraoperative hemostasis is crucial.
- Collaboration with pathologists is essential for accurate diagnosis.
Guideline-Based Recommendations
Diagnosis
- Utilize imaging techniques such as CT and MRI for initial assessment.
- Confirm diagnosis through histopathological analysis and molecular testing.
Management
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Surgical intervention is critical; careful monitoring post-surgery is necessary.
Clinical Best Practices
- Ensure thorough preoperative evaluation and imaging.
- Maintain a multidisciplinary approach involving surgeons and pathologists.
- Monitor for neurological deficits postoperatively.
- Collaborate with pathologists for accurate diagnosis.
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