Temporal trends in clinical and inflammatory features of Kawasaki disease across the COVID-19 pandemic: a single-center experience from Turkey - Scorecard - MDSpire
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Temporal trends in clinical and inflammatory features of Kawasaki disease across the COVID-19 pandemic: a single-center experience from Turkey
Clinical Scorecard: Shifts in Clinical and Inflammatory Characteristics of Kawasaki Disease During the COVID-19 Pandemic: Insights from a Turkish Single-Center Study
At a Glance
Category
Detail
Condition
Kawasaki Disease
Key Mechanisms
Acute, self-limited febrile vasculitis of childhood with potential infectious triggers.
Target Population
Children diagnosed with Kawasaki disease.
Care Setting
Pediatric departments and cardiology units.
Key Highlights
Increased C-reactive protein and erythrocyte sedimentation rate during the pandemic.
Higher frequency of thrombocytosis and lower occurrence of cervical lymphadenopathy in the pandemic period.
Shorter time to diagnosis and more clinical findings in the post-pandemic period.
No significant differences in coronary artery involvement across periods.
Study excluded cases of multisystem inflammatory syndrome in children (MIS-C).
Guideline-Based Recommendations
Diagnosis
Diagnosis based on 2017 American Heart Association criteria.
Management
Intravenous immunoglobulin treatment as standard care.
Monitoring & Follow-up
Echocardiography performed at diagnosis and during follow-up.
Risks
Potential for coronary artery aneurysm or dilatation.
Patient & Prescribing Data
Children diagnosed with Kawasaki disease from 2015 to 2024.
Treatment response and outcomes were similar across pre-pandemic, pandemic, and post-pandemic periods.
Clinical Best Practices
Regular monitoring of inflammatory markers and echocardiographic outcomes.
