Preoperative 18F-FDG PET/CT as a surgical triage tool for synchronous neoplasm detection in acute left-sided obstructive colorectal cancer: a two-institution retrospective cohort study - Scorecard - MDSpire
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Utilizing Preoperative 18F-FDG PET/CT for Surgical Decision-Making in Identifying Synchronous Neoplasms in Acute Left-Sided Obstructive Colorectal Cancer: A Retrospective Study Across Two Institutions
Clinical Scorecard: Utilizing Preoperative 18F-FDG PET/CT for Surgical Decision-Making in Identifying Synchronous Neoplasms in Acute Left-Sided Obstructive Colorectal Cancer: A Retrospective Study Across Two Institutions
At a Glance
Category
Detail
Condition
Acute Left-Sided Obstructive Colorectal Cancer
Key Mechanisms
Preoperative 18F-FDG PET/CT for detecting synchronous neoplasms
Target Population
Patients with acute left-sided obstructive colorectal adenocarcinoma
Care Setting
Tertiary referral centers
Key Highlights
Sensitivity for invasive sCRC was 77.8%, specificity 95.0%
Sensitivity for CSN was 52.9%, specificity 96.2%
Only 1.5% of PET-negative patients had invasive sCRC
Secondary curative resection required in 3.4% of patients
PET/CT is not a substitute for clearing colonoscopy
Guideline-Based Recommendations
Diagnosis
Use preoperative 18F-FDG PET/CT to assess for synchronous neoplasms
Management
Consider additional intraoperative assessment if PET/CT is positive
Monitoring & Follow-up
Postoperative clearing colonoscopy within 6 months is recommended
Risks
Missed synchronous cancer may lead to delayed treatment and additional morbidity
Patient & Prescribing Data
149 consecutive patients with acute left-sided obstructive colorectal adenocarcinoma
PET/CT findings may influence surgical decision-making
Clinical Best Practices
Incorporate PET/CT findings into surgical planning
Perform clearing colonoscopy postoperatively for comprehensive evaluation
by Kyung Uk Jung, Sung Ryol Lee, Joosung Park, Hyung Ook Kim, Hungdai Kim, Hee-Sung Song, Ji Young Lee, Yong Bog Kim, Jaemin Jo, Ji Eun Park, Hyun Joo Song, Heung Up Kim, Weon Young Chang, Ho-kyung Chun, Donghyoun Lee