Breast milk Δ9-tetrahydrocannabinol in cannabis users during the postpartum period: correlation between breast milk, maternal urine and saliva samples during early lactation - Scorecard - MDSpire
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Breast milk Δ9-tetrahydrocannabinol in cannabis users during the postpartum period: correlation between breast milk, maternal urine and saliva samples during early lactation
Clinical Scorecard: Analysis of Δ9-tetrahydrocannabinol Levels in Breast Milk of Cannabis Users During Early Lactation: A Study of Correlations with Maternal Urine and Saliva Samples
At a Glance
Category
Detail
Condition
Cannabis use during lactation
Key Mechanisms
Assessment of Δ9-THC concentrations in breast milk, saliva, and urine
Target Population
Postpartum women with cannabis use at delivery
Care Setting
Vall d’Hebron University Hospital, Barcelona, Spain
Key Highlights
Δ9-THC concentrations in breast milk decreased rapidly after postpartum cannabis cessation.
Urinary THC-COOH concentrations remained quantifiable longer than breast milk Δ9-THC.
Salivary Δ9-THC showed limited concordance with breast milk Δ9-THC.
Guideline-Based Recommendations
Diagnosis
Assessment of cannabis use through urine testing at delivery.
Management
Counseling on the potential risks of cannabis use during breastfeeding.
Monitoring & Follow-up
Regular monitoring of Δ9-THC levels in breast milk and urine.
Risks
Potential psychotropic effects on infants due to Δ9-THC exposure.
Patient & Prescribing Data
Postpartum women who used cannabis at delivery.
Abstinence from cannabis during breastfeeding is recommended.
Clinical Best Practices
Provide evidence-based counseling to breastfeeding women regarding cannabis use.
Monitor Δ9-THC levels in breast milk for women with recent cannabis use.
by Miguel Sandonís, Maia Brik, Clara Ramirez, Laura Castellote, Anna Creus, Gemma Parramón, Anna Suy, Josep Antoni Ramos-Quiroga, Raul Felipe Palma-Álvarez, Constanza Daigre
