Chemotherapy-related cognitive impairment and non-pharmacological interventions targeting the nervous system: a systematic review - Scorecard - MDSpire

Chemotherapy-related cognitive impairment and non-pharmacological interventions targeting the nervous system: a systematic review

  • By

  • Norbert Dosa

  • Intouch Limvaree

  • Camila Bonin Pinto

  • Faddi Saleh Velez

  • Zalan Kaposzta

  • Zsofia Szarvas

  • Zachary C. Pope

  • Anna Csiszar

  • Wajeeha Razaq

  • Ryan D. Nipp

  • Andriy Yabluchanskiy

  • Peter Mukli

  • June 2, 2026

  • 0 min

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Clinical Scorecard: Cognitive Dysfunction Associated with Chemotherapy and Non-Pharmacological Strategies for Nervous System Support: A Systematic Review

At a Glance

CategoryDetail
Condition
Key MechanismsNeuroinflammation, cerebrovascular endothelium senescence, blood-brain barrier disruption related to CRCI.
Target Population
Care Setting

Key Highlights

  • highlight_2

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Regularly evaluate cognitive outcomes using standardized cognitive assessments in cancer survivors post-chemotherapy.

      Risks

        Patient & Prescribing Data

        Cancer survivors with chemotherapy-related cognitive impairment.

        Non-invasive interventions may have lower side effect profiles compared to pharmacological agents.

        Clinical Best Practices

        • best_practice_2

        Related Resources & Content

        Original Source(s)

        Chemotherapy-related cognitive impairment and non-pharmacological interventions targeting the nervous system: a systematic review

        • by Norbert Dosa, Intouch Limvaree, Camila Bonin Pinto, Faddi Saleh Velez, Zalan Kaposzta, Zsofia Szarvas, Zachary C. Pope, Anna Csiszar, Wajeeha Razaq, Ryan D. Nipp, Andriy Yabluchanskiy, Peter Mukli

        • June 2, 2026

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