Analysis of latent profiles of stressors and their influencing factors in patients with breast cancer undergoing postoperative chemotherapy: a mixed-methods study - Scorecard - MDSpire
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Investigation of Hidden Stressor Profiles and Contributing Factors in Breast Cancer Patients Receiving Postoperative Chemotherapy: A Mixed-Methods Approach

  • By

  • Jingjing Chen

  • Tiantian Yang

  • Xiaoling Yan

  • August 21, 2026

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Clinical Scorecard: Investigation of Hidden Stressor Profiles and Contributing Factors in Breast Cancer Patients Receiving Postoperative Chemotherapy: A Mixed-Methods Approach

At a Glance

CategoryDetail
ConditionBreast Cancer
Key MechanismsPsychosocial stressors related to postoperative chemotherapy
Target PopulationPatients with breast cancer receiving postoperative chemotherapy
Care SettingOncology outpatient settings

Key Highlights

  • Four latent stress patterns identified: Low-stress Adaptive, Moderate-High Physio-Psychological Distress, High Medical Concerns, High-Stress Across Domains.
  • Age is a protective factor against moderate-high stress profiles.
  • Stage III breast cancer increases likelihood of high medical concerns and high-stress profiles.
  • Monthly family income ≤5000 RMB and treatment-related complications are associated with higher stress.
  • Qualitative themes include multiple stressors, depletion of psychological resources, and the impact of external support.

Guideline-Based Recommendations

Diagnosis

  • Utilize latent profile analysis to identify stress profiles among patients.

Management

  • Provide targeted psychosocial support based on identified stress profiles.

Monitoring & Follow-up

  • Regularly assess stress levels and profiles in patients undergoing chemotherapy.

Risks

  • Monitor for psychological distress, which may affect treatment adherence and clinical outcomes.

Patient & Prescribing Data

Patients with breast cancer undergoing postoperative chemotherapy.

Targeted assistance recommended for patients in high-stress profiles.

Clinical Best Practices

  • Implement individualized psychosocial interventions based on stress profile identification.
  • Enhance information and decision-making support for patients with high medical concerns.

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