Spontaneous splenic rupture in a patient with paratyphoid a fever: a case report and literature review
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By
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Fangwan Yang
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Zhi Kou
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Yin Zhang
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Xiaohuan Wu
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Yuyu Zhu
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Man Chen
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Hongmei Li
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Shenghui Zhang
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Shide Lin
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Ying Li
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July 3, 2026
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Clinical Scorecard: Spontaneous Rupture of the Spleen in a Patient Diagnosed with Paratyphoid Fever: A Case Study and Review of Existing Literature
At a Glance
| Category | Detail |
| Condition | Spontaneous Splenic Rupture associated with Paratyphoid Fever |
| Key Mechanisms | Infection by Salmonella enterica serovar Paratyphi A leading to splenic complications |
| Target Population | Patients with enteric fever, particularly in high-endemic regions |
| Care Setting | Infectious disease department in a hospital |
Key Highlights
- Spontaneous splenic rupture (SSR) is a rare complication of enteric fever.
- Only six cases of SSR related to enteric fever have been reported in literature.
- The patient was managed nonoperatively and recovered uneventfully.
- Clinical vigilance is necessary for SSR in suspected enteric fever cases.
Guideline-Based Recommendations
Diagnosis
- Consider SSR in patients with high fever and abdominal pain, especially in endemic areas.
Management
- Nonoperative management may be sufficient for hemodynamically stable patients.
Monitoring & Follow-up
- Monitor for signs of peritonitis and hemodynamic stability.
Risks
- Mortality rate for SSR in enteric fever cases is approximately 33.3%.
Patient & Prescribing Data
15-year-old male with confirmed S. Paratyphi A infection
Antimicrobial susceptibility testing showed sensitivity to ceftriaxone, ciprofloxacin, and imipenem.
Clinical Best Practices
- Maintain clinical awareness of SSR in patients with enteric fever.
- Utilize imaging studies to confirm splenic involvement.
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