Development and validation of a predictive model for chronic or persistent immune thrombocytopenia in children incorporating anti-glycoprotein IIb antibody: a retrospective cohort study utilizing LASSO regression and bootstrap stability analysis - Scorecard - MDSpire

Development and validation of a predictive model for chronic or persistent immune thrombocytopenia in children incorporating anti-glycoprotein IIb antibody: a retrospective cohort study utilizing LASSO regression and bootstrap stability analysis

  • By

  • Ximei Yang

  • Xianghui Wan

  • Lei Ying

  • Xiaoying Chen

  • Zhiqiang Liu

  • Wei Huang

  • Jiangwei Ke

  • June 5, 2026

  • 0 min

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Clinical Scorecard: Creation and assessment of a predictive framework for chronic or persistent immune thrombocytopenia in pediatric patients, incorporating anti-glycoprotein IIb antibodies: a retrospective cohort analysis using LASSO regression and bootstrap stability methods

At a Glance

CategoryDetail
Condition
Key MechanismsAutoimmune destruction of platelets and compromised platelet production (source needed).
Target Population
Care Setting

Key Highlights

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Guideline-Based Recommendations

Diagnosis

    Management

    • R
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    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Children newly diagnosed with immune thrombocytopenia

        Integration of anti-platelet glycoprotein antibodies enhances predictive accuracy

        Clinical Best Practices

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        Related Resources & Content

        Original Source(s)

        Development and validation of a predictive model for chronic or persistent immune thrombocytopenia in children incorporating anti-glycoprotein IIb antibody: a retrospective cohort study utilizing LASSO regression and bootstrap stability analysis

        • by Ximei Yang, Xianghui Wan, Lei Ying, Xiaoying Chen, Zhiqiang Liu, Wei Huang, Jiangwei Ke

        • June 5, 2026

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