Geriatric nutritional risk Index predicts adverse outcomes across cardiovascular–kidney–metabolic syndrome: discovery in NHANES and external validation in CKM stage 4 patients undergoing PCI - Scorecard - MDSpire
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Geriatric nutritional risk Index predicts adverse outcomes across cardiovascular–kidney–metabolic syndrome: discovery in NHANES and external validation in CKM stage 4 patients undergoing PCI
Clinical Scorecard: Geriatric Nutritional Risk Index as a Predictor of Negative Outcomes in Cardiovascular–Kidney–Metabolic Syndrome: Findings from NHANES and Validation in Stage 4 CKM Patients Undergoing PCI
At a Glance
Category
Detail
Condition
Cardiovascular–kidney–metabolic syndrome
Key Mechanisms
Geriatric Nutritional Risk Index (GNRI) as a prognostic biomarker
Target Population
Adults with CKM syndrome, particularly Stage 4 patients undergoing PCI
Care Setting
Clinical cohort analysis and population-based study
Key Highlights
Lower GNRI is associated with higher hazards of all-cause and cardiovascular mortality.
Each 1-unit increase in GNRI correlates with a lower hazard of adverse outcomes.
GNRI provides incremental risk discrimination for major adverse cardiovascular events (MACE).
Risk rises sharply below GNRI ≈ 100.
GNRI is an inexpensive marker for identifying higher-risk patients.
Guideline-Based Recommendations
Diagnosis
Evaluate GNRI for prognostic assessment in CKM syndrome.
Management
Consider GNRI in risk stratification for patients undergoing PCI.
Monitoring & Follow-up
Monitor GNRI levels as part of comprehensive risk assessment in CKM patients.
Risks
Patients with lower GNRI are at increased risk for adverse cardiovascular outcomes.
Patient & Prescribing Data
CKM Stage 4 patients undergoing PCI
GNRI can aid in identifying patients at higher risk for negative outcomes.
Clinical Best Practices
Incorporate GNRI into routine assessments for CKM syndrome patients.
Utilize GNRI as a tool for risk stratification in clinical decision-making.
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