Effect and mechanism of repetitive transcranial magnetic stimulation of angular gyrus on patients with consciousness disorder
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By
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Linghui Dong
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Hui Li
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Kaiyue Han
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Zhiqing Tang
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Xingxing Liao
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Junzi Long
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Xinyue Liu
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Tao Lin
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Hao Zhang
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June 17, 2026
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Clinical Scorecard: Impact and Mechanisms of High-Frequency rTMS on the Angular Gyrus in Patients with Disorders of Consciousness
At a Glance
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| Key Mechanisms | Remove or rephrase to ensure direct support from the source. |
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Key Highlights
- Behavioral improvement occurred more frequently during active rTMS than sham stimulation (p < 0.05).
- Improvements were noted in visual, motor, and auditory domains.
- Stronger baseline within-DMN functional connectivity predicted greater likelihood of improvement (AUC = 0.972).
- Post-rTMS recovery within DMN and SCN characterized responders (AUC = 0.861).
- The study utilized a randomized, double-blind, sham-controlled crossover design.
Guideline-Based Recommendations
Diagnosis
Management
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Monitoring & Follow-up
Risks
Patient & Prescribing Data
Patients diagnosed with prolonged disorders of consciousness (pDoC).
Active rTMS may lead to significant behavioral improvements in a subset of patients.
Clinical Best Practices
Related Resources & Content
