Utilizing Explainable Machine Learning to Classify Hypertension Prevalence: A Cross-Sectional Analysis in Hainan Province, China
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By
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Yuewei Wu
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Shan Huang
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Miaomiao Qi
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Yuanyuan Zhang
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Mei Lu
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Tianfa Li
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Yueqiong Kong
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July 17, 2026
Clinical Scorecard: Utilizing Explainable Machine Learning to Classify Hypertension Prevalence: A Cross-Sectional Analysis in Hainan Province, China
At a Glance
| Category | Detail |
| Condition | Hypertension |
| Key Mechanisms | Explainable machine learning models for classification of hypertension prevalence. |
| Target Population | Permanent residents aged ≥18 years in Hainan Province, China. |
| Care Setting | Community health screening. |
Key Highlights
- 32.5% prevalence of hypertension identified in the study population.
- eXtreme Gradient Boosting (XGBoost) model achieved an AUC of 0.8461.
- Top predictors included age, smoking, urine microalbumin, and diabetes.
- SHAP and LIME algorithms used for model interpretability.
- Study supports enhanced hypertension screening and prevention strategies.
Guideline-Based Recommendations
Diagnosis
- Utilize machine learning models to classify hypertension status.
Management
- Implement screening programs based on machine learning findings.
Monitoring & Follow-up
- Regularly assess hypertension prevalence in community settings.
Risks
- Hypertension is a major risk factor for cardiovascular disease and stroke.
Patient & Prescribing Data
General population in Hainan Province, China.
Focus on early identification and preventive interventions for high-risk individuals.
Clinical Best Practices
- Incorporate explainable machine learning techniques in clinical practice.
- Enhance awareness programs for hypertension management.
- Utilize identified predictors for targeted screening efforts.
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