Development and validation of a nomogram to predict symptomatic recurrence following laparoscopic adenomyomectomy - Scorecard - MDSpire

Development and validation of a nomogram to predict symptomatic recurrence following laparoscopic adenomyomectomy

  • By

  • Yiwen Yao

  • Jilan Jiang

  • Jin Yu

  • Yeping Yang

  • Wenyu Li

  • Feng Sun

  • July 16, 2026

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Clinical Scorecard: Creation and assessment of a nomogram for forecasting symptomatic recurrence post-laparoscopic adenomyomectomy

At a Glance

CategoryDetail
ConditionSymptomatic recurrence after laparoscopic adenomyomectomy
Key MechanismsIndependent predictors include previous surgical history of ovarian endometrioma, preoperative CA125 level, concomitant ovarian endometrioma, postoperative medication modality, and duration of postoperative therapy.
Target PopulationWomen aged 20–45 years with dysmenorrhea and/or menorrhagia undergoing laparoscopic adenomyomectomy.
Care SettingDepartment of Gynecology, International Peace Maternity and Child Health Hospital

Key Highlights

  • Nomogram developed to predict symptomatic recurrence post-surgery.
  • Study included 484 patients with 131 experiencing recurrence.
  • Nomogram showed good discriminatory ability (AUC 0.776).
  • Calibration curve demonstrated good performance.
  • High net benefit for predicted probability thresholds between 0% and 60%.

Guideline-Based Recommendations

Diagnosis

  • Ultrasonographic diagnosis of adenomyosis based on MUSA criteria.

Management

  • Consider adjuvant postoperative hormonal suppression to reduce recurrence.

Monitoring & Follow-up

  • Postoperative follow-up to assess for symptomatic recurrence.

Risks

  • Recurrence rates can reach up to 49.0% by the second postoperative year.

Patient & Prescribing Data

Women aged 20–45 years with adenomyosis undergoing laparoscopic adenomyomectomy.

Postoperative hormonal suppression may improve symptom control and reduce recurrence.

Clinical Best Practices

  • Utilize nomograms for individualized risk estimation post-surgery.
  • Conduct thorough preoperative evaluations including CA125 levels.

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