Case Report: A literature review of the medical complications arising from etomidate-laced vapes and two case studies of hypokalemia associated with etomidate use - Scorecard - MDSpire

Case Report: A literature review of the medical complications arising from etomidate-laced vapes and two case studies of hypokalemia associated with etomidate use

  • By

  • Tian Ling Low

  • Christopher Cheng Soon Cheok

  • Melvyn Weibin Zhang

  • June 17, 2026

  • 0 min

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Clinical Scorecard: Case Study and Literature Review: Medical Issues Linked to Etomidate-Infused Vaping and Two Instances of Hypokalemia Related to Etomidate Usage

At a Glance

CategoryDetail
Condition
Key MechanismsInhibition of 11β-hydroxylase leading to adrenal dysfunction and mineralocorticoid excess
Target Population
Care Setting

Key Highlights

    Guideline-Based Recommendations

    Diagnosis

    • Screen for hypokalemia in patients with history of etomidate use

    Management

    • Referral to National Addictions Management Service for treatment

    Monitoring & Follow-up

    • Regular monitoring of serum potassium levels

    Risks

    • Risk of severe adrenal insufficiency and hypokalemic paralysis

    Patient & Prescribing Data

    Individuals with a history of etomidate-laced vaporizer use

    Approximately 40% of patients screened had hypokalemia, mostly asymptomatic

    Clinical Best Practices

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