Unexpected Outcomes of Intravenous Thrombolysis in a Patient with Aortic Dissection Undergoing Delayed Surgical Intervention Presenting as Acute Ischemic Stroke: A Case Study - Scorecard - MDSpire

Unexpected Outcomes of Intravenous Thrombolysis in a Patient with Aortic Dissection Undergoing Delayed Surgical Intervention Presenting as Acute Ischemic Stroke: A Case Study

  • By

  • Tomokazu Kosuga

  • Yukio Hosokawa

  • Hidetsugu Hori

  • Keiichiro Tayama

  • October 31, 2025

  • 0 min

Share

Clinical Scorecard: Unexpected Outcomes of Intravenous Thrombolysis in a Patient with Aortic Dissection Undergoing Delayed Surgical Intervention Presenting as Acute Ischemic Stroke: A Case Study

At a Glance

CategoryDetail
Condition
Key MechanismsIntravenous thrombolysis (IVT) may lead to complications in AAD, including new cerebral infarctions and increased risk of bleeding.
Target Population
Care Setting

Key Highlights

  • IVT is contraindicated in AAD due to risks of bleeding and uncertain efficacy.
  • Delayed aortic surgery was performed due to hemodynamic stability and absence of critical AAD manifestations.
  • New cerebral infarctions were detected post-IVT despite initial stability.
  • Patient recovery was successful with no new neurological deficits post-surgery.
  • Five-year follow-up shows the patient living independently.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Monitor neurological status and imaging for new infarctions post-IVT.
      • Consider follow-up imaging within 24 hours post-IVT to assess for complications.

      Risks

        Patient & Prescribing Data

        Careful assessment of risks associated with thrombolysis in AAD is crucial, especially in elderly patients with hypertension.

        Clinical Best Practices

        • Prioritize surgical intervention for AAD when indicated.
        • Assess hemodynamic stability before delaying surgery.
        • Monitor coagulation parameters post-thrombolysis, especially in patients with hypertension.

        References

        Original Source(s)

        Related Content