Preoperative neutrophil-to-lymphocyte ratio and systemic immune-inflammation index as prognostic biomarkers for postoperative pneumonia and pulmonary complications after thoracic surgery: a systematic review and meta-analysis - Scorecard - MDSpire

Preoperative neutrophil-to-lymphocyte ratio and systemic immune-inflammation index as prognostic biomarkers for postoperative pneumonia and pulmonary complications after thoracic surgery: a systematic review and meta-analysis

  • By

  • Xinrui Yin

  • Shijia Du

  • June 5, 2026

  • 0 min

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Clinical Scorecard: Prognostic Value of Preoperative Neutrophil-to-Lymphocyte Ratio and Systemic Immune-Inflammation Index for Postoperative Pneumonia and Pulmonary Complications Following Thoracic Surgery: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
Condition
Key MechanismsNeutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) as immune-inflammatory biomarkers, as reported in the study.
Target Population
Care Setting

Key Highlights

    Guideline-Based Recommendations

    Diagnosis

    • Preoperative assessment of NLR and SII may provide additional prognostic information, as suggested by the study.

    Management

    • Consideration of NLR and SII in risk stratification for postoperative pneumonia, as indicated in the study.

    Monitoring & Follow-up

    • Further studies needed to validate NLR and SII as routine monitoring tools, as noted in the study.

    Risks

    • Increased risk of postoperative pneumonia and pulmonary complications associated with higher NLR and SII, as reported in the study.

    Patient & Prescribing Data

    Adults undergoing thoracic surgery, specifically lung resection or esophagectomy.

    NLR and SII are low-cost indices derived from routine blood counts, requiring no additional laboratory costs.

    Clinical Best Practices

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