The Association Between Depression and Gastro-Oesophageal Reflux Disease (GERD): Findings from the UK Biobank Analysis - Scorecard - MDSpire

The Association Between Depression and Gastro-Oesophageal Reflux Disease (GERD): Findings from the UK Biobank Analysis

  • By

  • Julia Reizner

  • Dennis Freuer

  • Timo Schmitz

  • Jakob Linseisen

  • Christa Meisinger

  • January 8, 2026

  • 0 min

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Clinical Scorecard: The Association Between Depression and Gastro-Oesophageal Reflux Disease (GERD): Findings from the UK Biobank Analysis

At a Glance

CategoryDetail
Condition
Key MechanismsLower oesophageal sphincter dysfunction leading to acid reflux and potential mucosal damage, as supported by study findings.
Target Population
Care Setting

Key Highlights

  • 0

Guideline-Based Recommendations

Diagnosis

    Management

    • Consider mental health status in GERD management plans, including specific treatment options such as lifestyle changes and medications.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        SSRIs may impact gastrointestinal function by altering gut motility and increasing acid secretion.

        Clinical Best Practices

        • 1

        References

        Original Source(s)

        The Association Between Depression and Gastro-Oesophageal Reflux Disease (GERD): Findings from the UK Biobank Analysis

        • by Julia Reizner, Dennis Freuer, Timo Schmitz, Jakob Linseisen, Christa Meisinger

        • January 8, 2026

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