Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States - Scorecard - MDSpire
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Impact of Race and Family Income on Health Outcomes in Pediatric Patients with Antineutrophil Cytoplasmic Antibody–Associated Vasculitis in U.S. Hospitals

  • By

  • Roberto Alejandro Valdovinos

  • William Daniel Soulsby

  • Emily von Scheven

  • June 2, 2026

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Clinical Scorecard: Impact of Race and Family Income on Health Outcomes in Pediatric Patients with Antineutrophil Cytoplasmic Antibody–Associated Vasculitis in U.S. Hospitals

At a Glance

CategoryDetail
ConditionAntineutrophil cytoplasmic antibody–associated vasculitis (AAV)
Key MechanismsSocial determinants of health (SDoH) including race and household income impact health outcomes.
Target PopulationPediatric patients hospitalized with AAV in the United States.
Care SettingPediatric inpatient care

Key Highlights

  • First study using nationally representative data to evaluate disparities in health outcomes across race and ethnicity and household income in pediatric AAV.
  • Hispanic ethnicity associated with severe AAV disease and end-stage renal disease (ESRD).
  • Lower household income linked to decreased odds of renal transplantation among ESRD patients.
  • Each income quartile increase correlates with an 85% increase in odds of renal transplantation.
  • Study includes the largest cohort of Black and Hispanic pediatric patients with AAV.

Guideline-Based Recommendations

Diagnosis

  • Utilize ICD-10-CM codes for identifying AAV in pediatric patients.

Management

  • Involve rheumatologists in managing social needs of patients with AAV.

Monitoring & Follow-up

  • Monitor socioeconomic factors as they may influence clinical outcomes in AAV.

Risks

  • Consider the impact of race and income on the likelihood of severe disease and renal outcomes.

Patient & Prescribing Data

Pediatric patients under 20 years with AAV.

Socioeconomic status may affect treatment access and outcomes.

Clinical Best Practices

  • Assess social determinants of health in pediatric patients with AAV.
  • Address financial insecurity as a barrier to healthcare access.

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