Serum uric acid levels and cardiorenal complication prevalence in hypertensive patients before and after the COVID-19 pandemic: a retrospective cross-sectional study from a tertiary traditional Chinese medicine hospital - Scorecard - MDSpire
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Serum uric acid levels and cardiorenal complication prevalence in hypertensive patients before and after the COVID-19 pandemic: a retrospective cross-sectional study from a tertiary traditional Chinese medicine hospital
Clinical Scorecard: Assessment of Serum Uric Acid Concentrations and the Incidence of Cardiorenal Complications in Hypertensive Individuals Pre- and Post-COVID-19 Pandemic: A Retrospective Cross-Sectional Analysis from a Tertiary Traditional Chinese Medicine Facility
At a Glance
Category
Detail
Condition
Hyperuricemia in hypertensive patients
Key Mechanisms
Endothelial dysfunction, activation of RAAS, NLRP3 inflammasome-mediated inflammation
Target Population
Hypertensive adults
Care Setting
Tertiary Traditional Chinese Medicine Facility
Key Highlights
Post-pandemic patients had higher mean SUA levels (448.70 μmol/L vs 422.39 μmol/L)
Increased prevalence of hyperuricemia post-pandemic (65.9% vs 52.1%)
Higher prevalence of cardiorenal complications post-pandemic (74.1% vs 49.1%)
Significant multiplicative interaction between hyperuricemia and post-pandemic period on cardiorenal risk
Routine SUA monitoring and proactive urate management recommended
Guideline-Based Recommendations
Diagnosis
Hyperuricemia defined as SUA >420 μmol/L
Management
Proactive urate management in hypertensive patients
Monitoring & Follow-up
Routine monitoring of serum uric acid levels
Risks
Increased risk of chronic kidney disease, heart failure, stroke, and atrial fibrillation
Patient & Prescribing Data
Hypertensive adults from Pu’er City Hospital
Consider lifestyle modifications and dietary adjustments to manage SUA levels
Clinical Best Practices
Assess SUA levels regularly in hypertensive patients
Evaluate lifestyle factors contributing to hyperuricemia
