Association between air pollution and incident cardiovascular diseases among a population with cardiovascular-kidney-metabolic syndrome stages 0–3: the first evidence from the China Health and Retirement Longitudinal Study - Scorecard - MDSpire

Association between air pollution and incident cardiovascular diseases among a population with cardiovascular-kidney-metabolic syndrome stages 0–3: the first evidence from the China Health and Retirement Longitudinal Study

  • By

  • Hongbo Huang

  • Yunhai Li

  • Ze Zhang

  • Yijing Xu

  • Linfeng Xie

  • Ying Huang

  • Tingting Wei

  • Haonan Pan

  • Zhiqi Hu

  • Zhen Gong

  • Jiaying Li

  • Yichen Wang

  • Aijie Zhang

  • Fan Li

  • June 23, 2026

  • 0 min

Share

Clinical Scorecard: Link Between Air Quality and New Cardiovascular Disease Cases in Individuals with Stages 0–3 of Cardiovascular-Kidney-Metabolic Syndrome: Initial Findings from the China Health and Retirement Longitudinal Study

At a Glance

CategoryDetail
ConditionCardiovascular-Kidney-Metabolic Syndrome
Key MechanismsProlonged exposure to air pollution, specifically PM1, PM2.5, PM10, and NO2, increases the risk of cardiovascular diseases.
Target PopulationMiddle-aged and older Chinese adults with CKM syndrome stages 0–3.
Care SettingPopulation-based cohort study.

Key Highlights

  • 21.8% of individuals with CKM syndrome experienced CVD events during a 7-year follow-up.
  • Each 10-μg/m3 increase in PM1, PM2.5, PM10, and NO2 was associated with increased CVD risk.
  • Lower educational attainment was linked to greater risk of CVD associated with air pollution exposure.
  • Metabolic syndrome partially mediated the relationship between air pollution and CVD.

Guideline-Based Recommendations

Diagnosis

  • Evaluate cardiovascular disease risk in individuals with CKM syndrome stages 0–3.

Management

  • Focus on managing modifiable risk factors to prevent CVD events.

Monitoring & Follow-up

  • Monitor air pollution exposure levels in at-risk populations.

Risks

  • Increased risk of CVD associated with prolonged exposure to air pollutants.

Patient & Prescribing Data

Individuals with CKM syndrome stages 0–3.

Consider environmental factors, such as air quality, in the management of cardiovascular risks.

Clinical Best Practices

  • Integrate air quality assessments into cardiovascular risk evaluations.
  • Target interventions for populations with lower educational attainment.

Related Resources & Content

Original Source(s)

Related Content