Association of SIRI and NLPR with post-operative pneumonia in middle-aged and elderly patients after hip fracture surgery - Scorecard - MDSpire

Association of SIRI and NLPR with post-operative pneumonia in middle-aged and elderly patients after hip fracture surgery

  • By

  • Yan Tan

  • Fang Chai

  • July 1, 2026

  • 0 min

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Clinical Scorecard: Link Between SIRI and NLPR Levels and Post-Operative Pneumonia in Middle-Aged and Elderly Individuals Following Hip Fracture Surgery

At a Glance

CategoryDetail
ConditionPost-operative pneumonia (POP)
Key MechanismsSystemic Inflammation Response Index (SIRI) and Neutrophil-to-Lymphocyte-to-Platelet Ratio (NLPR)
Target PopulationMiddle-aged and elderly patients aged 45 years or older
Care SettingPost-operative care following hip fracture surgery

Key Highlights

  • 5.53% of patients developed post-operative pneumonia after hip fracture surgery.
  • Both SIRI and NLPR are positively associated with the risk of pneumonia.
  • NLPR above 2.879 is significantly associated with increased incidence of POP (OR = 5.47).
  • Moderate discriminative performance for both markers (AUC: 0.701 for SIRI, 0.738 for NLPR).

Guideline-Based Recommendations

Diagnosis

  • Evaluate SIRI and NLPR levels at admission for risk assessment of post-operative pneumonia.

Management

    Monitoring & Follow-up

      Risks

      • Post-operative pneumonia is a common complication with significant morbidity and mortality.

      Patient & Prescribing Data

      Patients aged 45 years or older undergoing hip fracture surgery.

      Clinical Best Practices

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