Clinical Scorecard: Efficacy of Different Exercise Modalities on Arterial Stiffness and Endothelial Function in Older Adults: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

At a Glance

Key Highlights

• Whole-body vibration and resistance training enhance endothelial function.
• Aerobic training and walking improve arterial stiffness.
• Stretching may reduce systolic blood pressure.
• Combined training is effective in lowering diastolic blood pressure.
• Moderate-to-high certainty of evidence for endothelial function outcomes.

Guideline-Based Recommendations

Diagnosis

• Assess arterial stiffness and endothelial function in older adults.

Management

• Implement exercise training tailored to individual phenotypic characteristics.

Monitoring & Follow-up

• Continuous monitoring of exercise intensity during training.

Risks

• Potential for bias and heterogeneity in study results.

Patient & Prescribing Data

Older adults with vascular ageing and elevated arterial stiffness.

Exercise modalities should be selected based on specific vascular outcomes.

Clinical Best Practices

• Integrate exercise as a cornerstone non-pharmacological strategy.
• Consider individual patient characteristics when prescribing exercise.

Related Resources & Content

• Systematic Review Registration