Editorial: Integrating nutrition in cancer therapy: approaches to improve patient outcomes and survival
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By
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Aurora Mirabile
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Nerina Denaro
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Vanesa Gregorc
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June 10, 2026
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Clinical Scorecard: Incorporating Nutritional Strategies in Cancer Treatment to Enhance Patient Outcomes and Survival Rates
At a Glance
| Category | Detail |
|---|
| Condition | Cancer |
| Key Mechanisms | Nutritional strategies impact metabolism, immune function, and treatment response. |
| Target Population | Oncology patients, particularly those with head and neck and gastrointestinal malignancies. |
| Care Setting | Clinical oncology settings. |
Key Highlights
- Malnutrition and metabolic dysregulation are prevalent in oncology patients.
- Early weight loss exceeding 5% is linked to poorer progression-free survival.
- Nutritional screening and risk stratification are critical in oncology.
- Proactive nutritional management is recommended within 24 hours post-surgery.
- Sustained nutritional support is associated with improved survival outcomes.
Guideline-Based Recommendations
Diagnosis
- Systematic malnutrition screening using validated tools.
Management
- Initiate enteral nutrition when oral intake is inadequate.
- Commence nutritional support within 24 hours after surgery.
- Weekly dietitian consultations during radiotherapy.
Monitoring & Follow-up
- Interdisciplinary models of care with dietitian involvement before and after surgery.
Risks
- Treatment-related toxicities exacerbate nutritional impairment.
Patient & Prescribing Data
Patients undergoing cancer treatment, especially those at risk of malnutrition.
Specific targets for protein intake (1.2–1.5 g/kg/day) and energy intake (≥30 kcal/kg/day) are recommended.
Clinical Best Practices
- Consider nutrition as a core component of oncologic care.
- Implement early nutritional interventions preceding surgery or chemoradiotherapy.
- Utilize high-protein oral supplementation to reduce postoperative complications.
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