Desflurane combined with ciprofol or esketamine improves postoperative symptoms without compromising early neurocognitive recovery after intracranial aneurysm endovascular coiling - Scorecard - MDSpire
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Desflurane combined with ciprofol or esketamine improves postoperative symptoms without compromising early neurocognitive recovery after intracranial aneurysm endovascular coiling
Clinical Scorecard: Effects of Desflurane with Ciprofol or Esketamine on Postoperative Outcomes and Neurocognitive Recovery Following Endovascular Coiling for Intracranial Aneurysms
At a Glance
Category
Detail
Condition
Key Mechanisms
Target Population
Patients aged 20–80 years with ASA I–III undergoing endovascular coiling for aSAH.
Care Setting
Key Highlights
Desflurane + esketamine provided superior analgesia compared to desflurane + ciprofol (adjusted p = 0.026).
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Monitor for postoperative nausea and vomiting (PONV), dizziness, pain scores, and the need for rescue antiemetics.
Risks
Patient & Prescribing Data
Desflurane + ciprofol reduces PONV and dizziness; desflurane + esketamine offers better pain control but may have higher PONV.
Clinical Best Practices
Utilize multimodal anesthesia strategies to enhance perioperative safety and recovery, supported by evidence from recent studies.
