Evaluation of nosocomial infections after congenital heart surgery in children: A comprehensive analysis including the systemic immune-inflammation index (SII) - Scorecard - MDSpire

Evaluation of nosocomial infections after congenital heart surgery in children: A comprehensive analysis including the systemic immune-inflammation index (SII)

  • By

  • Tak, Sercan

  • Demirdağ, Tuğba Bedir

  • İriz, Erkan

  • Yiğiter, Eda Nur

  • Shide, Issa Aden Ahmed

  • Mammadov, Subhan

  • Tapısız, Anıl

  • Canbeyli, Fatma Hayvacı

  • Yazıcı, Mutlu Uysal

  • Azapağası, Ebru

  • April 29, 2026

  • 0 min

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Clinical Scorecard: Assessment of Hospital-Acquired Infections in Pediatric Patients Post-Congenital Heart Surgery: An In-Depth Study of the Systemic Immune-Inflammation Index (SII)

At a Glance

CategoryDetail
ConditionHospital-Acquired Infections (NIs) in Pediatric Patients Post-Congenital Heart Surgery
Key MechanismsIndependent risk factors include younger age, mechanical ventilation duration, postoperative length of stay, and presence of postoperative complications.
Target PopulationChildren with congenital heart disease undergoing cardiovascular surgery
Care SettingSingle-center hospital setting

Key Highlights

  • 22.0% of patients developed nosocomial infections post-surgery.
  • Sepsis (69.6%) and pneumonia (30.4%) were the most frequent types of NIs.
  • Gram-negative bacteria were predominant in infections (58.4%).
  • Postoperative complications are the strongest predictor of NIs.
  • Postoperative SII did not retain strong independent predictive value.

Guideline-Based Recommendations

Diagnosis

  • NIs defined based on CDC/NHSN criteria.

Management

  • Stringent infection control measures are necessary.

Monitoring & Follow-up

  • Monitor mechanical ventilation duration and postoperative length of stay.

Risks

  • Younger age, prolonged mechanical ventilation, and postoperative complications significantly increase NI risk.

Patient & Prescribing Data

209 children who underwent cardiovascular surgery and remained hospitalized for >48 hours.

Postoperative complications significantly increase the risk of NIs.

Clinical Best Practices

  • Aggressive management of postoperative morbidity is essential.

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