Growth-adjusted reference values for the main pulmonary artery-to-ascending aorta ratio derived from clinically indicated chest CT in children - Scorecard - MDSpire
Clinical Scorecard: Reference Values for the Main Pulmonary Artery to Ascending Aorta Ratio Adjusted for Growth Based on Chest CT in Pediatric Patients
At a Glance
Category
Detail
Condition
Pulmonary Hypertension (PH)
Key Mechanisms
Elevated pulmonary vascular resistance (PVR) and increased right heart burden
Target Population
Pediatric patients under 18 years
Care Setting
Pediatric medical centers
Key Highlights
MPA/AA ratio is a supportive marker in evaluating PH in children.
Current pediatric recommendations rely on absolute MPA/AA thresholds.
Growth-adjusted reference values for MPA/AA are needed for accurate interpretation.
Study includes a modeling cohort and an independent RHC cohort.
CT examinations were performed using various scanners and protocols.
Guideline-Based Recommendations
Diagnosis
Right heart catheterization (RHC) is the reference standard for diagnosis.
Management
Monitoring & Follow-up
Risks
Examinations excluded if known conditions affecting pulmonary vascular hemodynamics are present.
Patient & Prescribing Data
Children without known conditions affecting pulmonary arterial morphology.
CT-derived MPA/AA measurements are used for risk stratification.
Clinical Best Practices
Use growth-adjusted MPA/AA ratios for individual interpretation in children.
Ensure adequate image quality for reliable MPA/AA measurement.
