Describing Patient Characteristics, Treatment Patterns, and Disease Burden Among Patients with Alopecia Areata in Mexico: A Secondary Analysis of the Adelphi Real World Alopecia Areata Disease Specific Programme - Scorecard - MDSpire
Conexiant’s news site is now MDSpire News. Learn more
Advertisement
Patient Profiles, Treatment Approaches, and Disease Burden in Alopecia Areata in Mexico: Secondary Analysis of the Adelphi Real World Disease-Specific Programme
Clinical Scorecard: Patient Profiles, Treatment Approaches, and Disease Burden in Alopecia Areata in Mexico
At a Glance
Category
Detail
Condition
Clinical topic addressed by the source article: Patient Profiles, Treatment Approaches, and Disease Burden in Alopecia Areata in Mexico
Key Mechanisms
Mechanisms or clinical associations described in the source article.
Target Population
Population described in the source article.
Care Setting
Linked cross-sectional physician and patient surveys, with retrospective data collection elements, conducted in Mexico from October 2024 to April 2025.
Key Highlights
Patients with moderate to very severe AA had greater clinical involvement, including more extensive scalp and nonscalp hair loss, impaired quality of life, and higher anxiety and depression levels.
Treatment across severity categories primarily comprised conventional therapies, especially corticosteroids.
Advanced therapies were infrequently used, including among patients with severe/very severe AA.
Patients with severe/very severe AA reported lower treatment satisfaction than those with mild or moderate disease.
The authors identify substantial unmet treatment needs and suggest potential access and reimbursement barriers in Mexico.
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Risks
The article states that conventional AA treatments generally have limited efficacy and are associated with adverse effects that restrict long-term use.
The article reports limited access in Latin America, including Mexico, to JAK inhibitors and other advanced therapies, as well as certain conventional options such as systemic corticosteroids, because public healthcare systems do not routinely reimburse these treatments.
Patient & Prescribing Data
Adults aged 18 years or older with diagnosed AA in Mexico. The source excerpt does not provide enough information to verify the patient sampling sequence or severity quotas.
Clinical Best Practices
The study reports that patients with moderate to very severe AA had greater clinical involvement, impaired quality of life, and higher anxiety and depression levels.
The cited 2013 Mexican guidelines specify intralesional corticosteroids as first-line treatment and potent topical corticosteroids as an alternative.
The cited guidelines list topical immunotherapy, minoxidil, phototherapy or photochemotherapy, and systemic therapies for refractory or more extensive disease.
The article notes that conventional treatments may have limited efficacy and adverse effects that restrict long-term use.
by Luis E. Sanchez-Duenas, Ashley S. Cha-Silva, Peter Anderson, Martha Alicia Aceves-Villalvazo, Veronica J. Guajardo-Barron, Carlos A. Barrera-Ochoa, Raul A. Becerra-Cerecedo, Jorge Alberto Barragan Garfias, William Jones, Samantha K. Kurosky, Nelly A. Espinoza-Gonzalez