Delayed Platelet Engraftment and Ongoing Pulmonary Infection Following Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation: A Case Study - Scorecard - MDSpire

Delayed Platelet Engraftment and Ongoing Pulmonary Infection Following Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation: A Case Study

  • By

  • Ying He

  • Yaxin Xiong

  • Juanjuan Zhang

  • Xinyu Gan

  • Fangyi Fan

  • Hai Yi

  • April 24, 2026

  • 0 min

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Clinical Scorecard: Delayed Platelet Engraftment and Ongoing Pulmonary Infection Following Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation: A Case Study

At a Glance

CategoryDetail
Condition
Key MechanismsInvasive fungal infection, bacterial superinfection (including Klebsiella pneumoniae) complicating engraftment.
Target Population
Care Setting

Key Highlights

  • Add: 'Patient developed multidrug-resistant Klebsiella pneumoniae superinfection on day +190.'

Guideline-Based Recommendations

Diagnosis

    Management

    • Administer antifungal and antibacterial therapies promptly, with a focus on multi-drug resistant infections.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Combination of antifungal, antibacterial, and antiviral prophylaxis is critical, especially in high-risk patients.

        Clinical Best Practices

        • Prioritize infection control measures before initiating PGF-directed therapies, with attention to multi-drug resistant organisms.

        References

        Original Source(s)

        Delayed Platelet Engraftment and Ongoing Pulmonary Infection Following Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation: A Case Study

        • by Ying He, Yaxin Xiong, Juanjuan Zhang, Xinyu Gan, Fangyi Fan, Hai Yi

        • April 24, 2026

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