Perception and willingness toward second-generation long-acting antipsychotics among patients with schizophrenia: a cross-sectional survey in Fujian, China - Scorecard - MDSpire

Perception and willingness toward second-generation long-acting antipsychotics among patients with schizophrenia: a cross-sectional survey in Fujian, China

  • By

  • Yixiang Zhou

  • Duoduo Lin

  • Haibin Zhang

  • Yinghua Huang

  • July 14, 2026

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Clinical Scorecard: Attitudes and Acceptance of Second-Generation Long-Acting Antipsychotics in Schizophrenia Patients: Findings from a Cross-Sectional Study in Fujian, China

At a Glance

CategoryDetail
ConditionSchizophrenia
Key MechanismsSecond-generation long-acting injectables (SGA-LAIs) improve medication adherence and reduce relapse rates.
Target PopulationPatients with schizophrenia attending outpatient follow-up visits at a tertiary psychiatric hospital.
Care SettingPsychiatric outpatient care

Key Highlights

  • 68.3% of participants expressed positive willingness to use SGA-LAIs.
  • Prior experience with SGA-LAIs significantly increased willingness to accept them.
  • Injection pain was the primary concern among those unwilling to accept SGA-LAIs.
  • Factors influencing acceptance included disease course and prior SGA-LAI experience.
  • Improving doctor-patient communication may enhance acceptance of SGA-LAIs.

Guideline-Based Recommendations

Diagnosis

  • Assess willingness to accept SGA-LAIs among patients with schizophrenia.

Management

  • Consider SGA-LAIs for patients with poor adherence and high relapse risk.

Monitoring & Follow-up

  • Monitor patient acceptance and experience with SGA-LAIs to optimize treatment.

Risks

  • Address concerns related to injection pain and needle aversion.

Patient & Prescribing Data

Patients with schizophrenia in outpatient settings.

Experience with SGA-LAIs and longer disease course correlate with greater willingness to accept treatment.

Clinical Best Practices

  • Enhance medication education for patients with a long disease course.
  • Strengthen doctor-patient communication regarding treatment options.
  • Improve initial patient experiences with SGA-LAIs to foster acceptance.

Related Resources & Content

    Original Source(s)

    Perception and willingness toward second-generation long-acting antipsychotics among patients with schizophrenia: a cross-sectional survey in Fujian, China

    • by Yixiang Zhou, Duoduo Lin, Haibin Zhang, Yinghua Huang

    • July 14, 2026

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