Dietary background, serum polyunsaturated fatty acid profiles, and 1-year outcomes after large-artery atherosclerotic stroke: a multicenter cohort study - Scorecard - MDSpire

Dietary background, serum polyunsaturated fatty acid profiles, and 1-year outcomes after large-artery atherosclerotic stroke: a multicenter cohort study

  • By

  • Xiaoci Lin

  • Zhihao Zhao

  • Daijun Zhu

  • Guogu Shen

  • Xuri Xu

  • Yinyan Li

  • July 10, 2026

  • 0 min

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Clinical Scorecard: Influence of Long-Term Dietary Habits and Serum Polyunsaturated Fatty Acid Levels on One-Year Outcomes Following Large-Artery Atherosclerotic Stroke: A Multicenter Cohort Analysis

At a Glance

CategoryDetail
ConditionLarge-Artery Atherosclerotic Cerebral Infarction (LAA-CI)
Key MechanismsLong-term dietary habits and serum polyunsaturated fatty acid profiles influence post-stroke outcomes.
Target PopulationPatients with ischemic stroke classified as LAA-CI.
Care SettingNeurology departments of tertiary hospitals.

Key Highlights

  • Patients with a high-fish/seafood diet showed better functional outcomes at 1-year follow-up.
  • Higher ω-6/ω-3 ratios were linked to increased risks of poor functional outcomes and cognitive impairment.
  • The study included 410 patients with LAA-CI and followed them for 1 year.

Guideline-Based Recommendations

Diagnosis

  • Diagnosis of ischemic stroke based on cranial MRI or CT.

Management

  • Consider dietary habits as a modifiable factor in post-stroke recovery.

Monitoring & Follow-up

  • Assess modified Rankin Scale (mRS) scores and NIHSS scores at follow-up.

Risks

  • Monitor for post-stroke depression and cognitive impairment, particularly in patients with higher ω-6/ω-3 ratios.

Patient & Prescribing Data

410 patients with ischemic stroke classified as LAA-CI.

Dietary modifications may be beneficial for improving post-stroke recovery outcomes.

Clinical Best Practices

  • Incorporate dietary assessments into post-stroke care plans.
  • Evaluate serum PUFA profiles for potential prognostic value.

Related Resources & Content

Original Source(s)

Dietary background, serum polyunsaturated fatty acid profiles, and 1-year outcomes after large-artery atherosclerotic stroke: a multicenter cohort study

  • by Xiaoci Lin, Zhihao Zhao, Daijun Zhu, Guogu Shen, Xuri Xu, Yinyan Li

  • July 10, 2026

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