Radially adjustable Tigertriever demonstrates higher reperfusion compared to self-expanding stent-retrievers during mechanical thrombectomy of large vessel occlusions: a systematic review and meta-analysis - Scorecard - MDSpire

Radially adjustable Tigertriever demonstrates higher reperfusion compared to self-expanding stent-retrievers during mechanical thrombectomy of large vessel occlusions: a systematic review and meta-analysis

  • By

  • Zain Tariq

  • Faizan Shahzad

  • Noor E. Jannat

  • Tallal Mushtaq Hashmi

  • Sonesh Amin

  • Mohammad AlMajali

  • Qasim Bashir

  • Jeffrey L. Saver

  • Besher Shami

  • Amit Chaudhari

  • July 1, 2026

  • 0 min

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Clinical Scorecard: Comparison of Radially Adjustable Tigertriever and Self-Expanding Stent-Retrievers for Enhanced Reperfusion in Mechanical Thrombectomy of Large Vessel Occlusions: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
ConditionAcute ischemic stroke due to large vessel occlusions
Key MechanismsComparison of radially adjustable Tigertriever and conventional self-expanding stent retrievers (SE-SRs) in mechanical thrombectomy
Target PopulationAdults with acute ischemic stroke undergoing mechanical thrombectomy
Care SettingInterventional neurovascular procedures

Key Highlights

  • Tigertriever achieved higher successful reperfusion rates (82.8% vs. 77.8%) compared to SE-SRs.
  • Procedural adverse events were lower with Tigertriever, but not statistically significant.
  • Rates of symptomatic intracranial hemorrhage, functional independence, and mortality were similar between groups.
  • The study included three retrospective cohort studies with a total of 476 patients.
  • Overall risk of bias was assessed as low to moderate.

Guideline-Based Recommendations

Diagnosis

  • Acute ischemic stroke diagnosis confirmed by imaging.

Management

  • Mechanical thrombectomy is the standard of care for large vessel occlusions.

Monitoring & Follow-up

  • Monitor for procedural adverse events and functional outcomes post-thrombectomy.

Risks

  • Potential risks include symptomatic intracranial hemorrhage and procedural adverse events.

Patient & Prescribing Data

Adults with acute ischemic stroke due to large vessel occlusions.

Tigertriever may offer improved reperfusion rates compared to SE-SRs.

Clinical Best Practices

  • Utilize radially adjustable devices like Tigertriever for tailored thrombectomy approaches.
  • Ensure comprehensive monitoring for complications post-procedure.

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