Patient Profiles and Outcomes in Endometriosis with Malignant or Borderline Ovarian Tumors: Insights from an ESGO Designated Center of Excellence - Scorecard - MDSpire

Patient Profiles and Outcomes in Endometriosis with Malignant or Borderline Ovarian Tumors: Insights from an ESGO Designated Center of Excellence

  • By

  • Maximilian Heinz Beck

  • Paul Kordowitzki

  • Eva Roser

  • Anna Trelinska-Finger

  • Emily Schoof

  • Lukas Chinczewski

  • Sylvia Mechsner

  • Jalid Sehouli

  • April 16, 2026

  • 0 min

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Clinical Scorecard: Patient Profiles and Outcomes in Endometriosis with Malignant or Borderline Ovarian Tumors: Insights from an ESGO Designated Center of Excellence

At a Glance

CategoryDetail
ConditionEndometriosis with malignant or borderline ovarian tumors
Key MechanismsEstrogen overstimulation, ARID1A mutation, PI3K/AKT/mTOR pathway activation
Target PopulationWomen of reproductive age with endometriosis and ovarian tumors
Care SettingTertiary academic medical center

Key Highlights

  • Endometriosis affects 5-10% of women of reproductive age.
  • Increased risk of ovarian cancer in women with deep infiltrating endometriosis.
  • Atypical endometriosis is a premalignant precursor lesion.
  • Endometriosis-associated ovarian cancer can show histopathologic transitions.
  • Survival outcomes evaluated in patients with malignant or borderline ovarian tumors.

Guideline-Based Recommendations

Diagnosis

  • Histologic confirmation of endometriosis during surgery for ovarian tumors.

Management

  • Consideration of endometriosis status in treatment planning for ovarian tumors.

Monitoring & Follow-up

  • Regular follow-up for disease recurrence in patients with endometriosis-associated tumors.

Risks

  • Increased risk of ovarian cancer associated with endometriosis.

Patient & Prescribing Data

Patients with malignant or borderline ovarian tumors and concurrent endometriosis.

Treatment strategies may vary based on endometriosis status and tumor characteristics.

Clinical Best Practices

  • Utilize a multidisciplinary approach for managing patients with endometriosis and ovarian tumors.
  • Incorporate genetic counseling for patients with a family history of ovarian cancer.

References

Original Source(s)

Patient Profiles and Outcomes in Endometriosis with Malignant or Borderline Ovarian Tumors: Insights from an ESGO Designated Center of Excellence

  • by Maximilian Heinz Beck, Paul Kordowitzki, Eva Roser, Anna Trelinska-Finger, Emily Schoof, Lukas Chinczewski, Sylvia Mechsner, Jalid Sehouli

  • April 16, 2026

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