Curative outcomes with metal-containing TCM in diabetic foot ulcers unresponsive to standard therapy: a case series
By
Yifan Zhang
Cai Yu
Xiaohan Qu
Qiannan Li
Guangyu Dai
Wanying Long
Hui Kong
Huihua Qu
Xuying Xu
Yue Zhang
Yan Zhao
May 8, 2026
Clinical Scorecard: Efficacy of Metal-Infused Traditional Chinese Medicine in Treating Diabetic Foot Ulcers Resistant to Conventional Therapies: A Case Series
At a Glance
Category Detail
Condition Diabetic Foot Ulcers (DFUs) Key Mechanisms Targeted debridement and regenerative stimulation Target Population Patients with refractory DFUs unresponsive to conventional therapies Care Setting Clinical management in a healthcare facility
Key Highlights
Topical Huafu Shengji ointment (HFSJO) demonstrated significant healing in chronic DFUs. All patients showed substantial granulation and epithelialization within 30–180 days. No significant adverse effects on liver or renal function were observed during treatment. Guideline-Based Recommendations
Diagnosis
Assess ulcer size, depth, and presence of infection. Utilize Wagner classification for ulcer staging. Management
Combine standard wound care with topical HFSJO treatment. Consider patient comorbidities and previous treatment responses. Monitoring & Follow-up
Regularly evaluate wound healing progress and signs of infection. Monitor blood glucose levels and overall patient health. Risks
Potential for recurrent infections and complications from chronic DFUs. Risk of amputation in severe cases. Patient & Prescribing Data
Patients with diabetes and chronic non-healing foot ulcers.
HFSJO may enhance healing in patients with poor response to conventional therapies.
Clinical Best Practices
Integrate traditional Chinese medicine with modern wound care strategies. Ensure comprehensive management of diabetes and associated comorbidities. Related Resources & Content
