The Role of Immune Cells and Cytokines in Radiation-Induced Damage: Key Functions and Potential Therapeutic Targets
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By
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Yanan Wu
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Yuanjing Tian
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YingYing Zhang
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Pingping Hu
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Lili Qiao
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Guodong Deng
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Ning Liang
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Yan Zhang
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Jiandong Zhang
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April 28, 2026
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Clinical Scorecard: The Role of Immune Cells and Cytokines in Radiation-Induced Damage: Key Functions and Potential Therapeutic Targets
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | Immune cell activation and cytokine release following ionizing radiation exposure, with a dual role in promoting and mitigating injury. |
| Target Population | |
| Care Setting | |
Key Highlights
- Limited FDA-approved agents exist for treating radiation exposure.
Guideline-Based Recommendations
Diagnosis
Management
- Implement supportive care and monitor for complications.
- Consider immune-based interventions, such as cytokine therapy or immune modulators, to enhance recovery.
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Individuals exposed to ionizing radiation, particularly those receiving radiotherapy.
Focus on restoring immune function and promoting tissue repair.
Clinical Best Practices
References
