Analysis of epicardial adipose tissue in relation to arterial hypertension using radiomics in photon-counting CT
By
Felix Waßmer
Jannik Barz
Dominik Nörenberg
Stefan O. Schoenberg
Alexander Hertel
Isabelle Ayx
July 15, 2026
Clinical Scorecard: Investigation of Epicardial Adipose Tissue and Its Correlation with Hypertension Through Radiomic Analysis in Photon-Counting CT
At a Glance
Category Detail
Condition Epicardial Adipose Tissue and Hypertension Key Mechanisms Radiomic analysis of epicardial adipose tissue using photon-counting CT to assess cardiovascular risk factors. Target Population Patients without coronary artery disease, aged 18 to 80 years. Care Setting Single-center retrospective study in a clinical imaging context.
Key Highlights
114 patients without coronary artery disease were analyzed. Lower mean epicardial adipose tissue attenuation was observed in the hypertension group. Logistic regression model achieved a cross-validated AUC of 0.65. Radiomics analysis provides objective quantification of cardiac structures. Integration of radiomics into cardiac CT is in early stages but shows potential. Guideline-Based Recommendations
Diagnosis
Use of cardiac CT for assessment of epicardial adipose tissue. Management
Consideration of radiomic features in cardiovascular risk stratification. Monitoring & Follow-up
Further validation of radiomic findings in larger cohorts. Risks
Challenges related to feature reproducibility and standardization. Patient & Prescribing Data
Patients with no evidence of coronary artery calcification or stenosis.
Exploratory findings suggest potential for individualized risk assessment.
Clinical Best Practices
Utilize advanced imaging techniques for accurate assessment of epicardial adipose tissue. Incorporate radiomics into routine cardiac imaging for enhanced risk stratification. Related Resources & Content
