Prevalence and associated factors of gestational diabetes mellitus among women with polycystic ovary syndrome: a systematic review and meta-analysis - Scorecard - MDSpire

Prevalence and associated factors of gestational diabetes mellitus among women with polycystic ovary syndrome: a systematic review and meta-analysis

  • By

  • Youchang Yuan

  • Liuxin Hu

  • Yanjing Li

  • Xinju Hou

  • July 17, 2026

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Clinical Scorecard: Assessment of Gestational Diabetes Mellitus Prevalence and Contributing Factors in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
ConditionGestational Diabetes Mellitus in Polycystic Ovary Syndrome
Key MechanismsInsulin resistance, pre-pregnancy BMI, gestational weight gain, family history of diabetes
Target PopulationWomen with Polycystic Ovary Syndrome
Care SettingClinical assessment and management of gestational diabetes

Key Highlights

  • Pooled GDM prevalence in PCOS is 24% with significant heterogeneity.
  • Primary prevalence estimate from cohort studies is 21.7%.
  • Associated factors include HOMA-IR, family history of diabetes, pre-pregnancy BMI, and gestational weight gain.

Guideline-Based Recommendations

Diagnosis

  • Utilize one-step and two-step methods for GDM diagnosis.

Management

  • Consider early monitoring of glucose metabolism and weight management in PCOS patients.

Monitoring & Follow-up

  • Regular assessment of glucose levels and weight during pregnancy.

Risks

  • Increased risk of fetal macrosomia, neonatal hypoglycemia, and long-term metabolic syndrome in offspring.

Patient & Prescribing Data

Women diagnosed with Polycystic Ovary Syndrome.

Management strategies should focus on monitoring and addressing metabolic risks.

Clinical Best Practices

  • Implement targeted screening for GDM in women with PCOS.
  • Utilize evidence-based guidelines for the diagnosis and management of GDM.

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