Hypnotic suggestibility as a moderator of treatment response in mild to moderate depression: an exploratory secondary analysis - Scorecard - MDSpire

Hypnotic suggestibility as a moderator of treatment response in mild to moderate depression: an exploratory secondary analysis

  • By

  • Julia Siewert

  • Benno Brinkhaus

  • Tatjana Tissen-Diabaté

  • Michael Teut

  • Nicolas Volz

  • July 2, 2026

  • 0 min

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Clinical Scorecard: The Role of Hypnotic Suggestibility in Influencing Treatment Outcomes for Mild to Moderate Depression: An Exploratory Secondary Analysis

At a Glance

CategoryDetail
ConditionMild to Moderate Depression
Key MechanismsHypnotic suggestibility as a potential moderator of treatment response.
Target PopulationPatients with mild to moderate depressive symptoms.
Care SettingRandomized controlled trial setting.

Key Highlights

  • Exploratory analysis of hypnotic suggestibility's role in treatment outcomes.
  • Participants included 94 individuals with mild to moderate depression.
  • No significant association found between suggestibility and symptom change.
  • Hypnotic suggestibility assessed using HGSHS-5:G and CIS.
  • Post hoc power analysis indicated insufficient group sizes for reliable detection.

Guideline-Based Recommendations

Diagnosis

  • Depressive symptoms measured using the Beck Depression Inventory–II.

Management

  • Consider hypnosis and PMR as interventions for depressive symptoms.

Monitoring & Follow-up

  • Monitor changes in depressive symptoms over time.

Risks

  • Limited statistical power may affect the reliability of findings.

Patient & Prescribing Data

Patients with mild to moderate depressive symptoms.

Further research needed to clarify treatment-response moderators.

Clinical Best Practices

  • Utilize standardized scales for assessing suggestibility in hypnosis research.
  • Consider both behavioral and imaginal aspects of suggestibility.

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