Gestational Exposure to 10 Classes of Priority Chemicals and Birth Outcomes in the ECHO Cohort - Scorecard - MDSpire

Gestational Exposure to 10 Classes of Priority Chemicals and Birth Outcomes in the ECHO Cohort

  • By

  • Jessie P. Buckley

  • Diana C. Pacyga

  • Xiaoshuang Xun

  • Dana Boyd Barr

  • Emily S. Barrett

  • Theresa Bastain

  • Deborah H. Bennett

  • Joseph M. Braun

  • Carrie V. Breton

  • Courtney Carignan

  • Lisa A. Croen

  • Anne L. Dunlop

  • Shohreh F. Farzan

  • Assiamira Ferrara

  • Frank D. Gilliland

  • Julie B. Herbstman

  • Margaret R. Karagas

  • Catherine J. Karr

  • Jordan R. Kuiper

  • John D. Meeker

  • Rachel L. Miller

  • Rachel Morello-Frosch

  • Thomas G. O’Connor

  • Jiwon Oh

  • Frederica P. Perera

  • Christina A. Porucznik

  • Megan E. Romano

  • Sheela Sathyanarayana

  • Susan L. Schantz

  • Rebecca J. Schmidt

  • Allison R. Sherris

  • Leonardo Trasande

  • Heather Volk

  • Deborah J. Watkins

  • Qi Zhao

  • Yeyi Zhu

  • Zhongmin Li

  • Edo Pellizzari

  • Kurunthachalam Kannan

  • Tracey J. Woodruff

  • Environmental influences on Child Health Outcomes (ECHO) Cohort Consortium

  • P Brian Smith

  • L Kristin Newby

  • Linda Adair

  • Lisa P. Jacobson

  • Diane Catellier

  • Monica McGrath

  • Christian Douglas

  • Priya Duggal

  • Emily Knapp

  • Amii Kress

  • Courtney K. Blackwell

  • Maxwell A. Mansolf

  • Jin-Shei Lai

  • Emily Ho

  • David Cella

  • Richard Gershon

  • Michelle L. Macy

  • Suman R. Das

  • Jane E. Freedman

  • Simon A. Mallal

  • John A. McLean

  • Ravi V. Shah

  • Meghan H. Shilts

  • Akram N. Alshawabkeh

  • Jose F. Cordero

  • John Meeker

  • Carlos A. Camargo

  • Kohei Hasegawa

  • Zhaozhong Zhu

  • Ashley F. Sullivan

  • Dana Dabelea

  • Wei Perng

  • Traci A. Bekelman

  • Greta Wilkening

  • Sheryl Magzamen

  • Brianna F. Moore

  • Anne P. Starling

  • Deborah J. Rinehart

  • Daphne Koinis Mitchell

  • Viren D'Sa

  • Sean C.L. Deoni

  • Hans-Georg Mueller

  • Cristiane S. Duarte

  • Catherine Monk

  • Glorisa Canino

  • Jonathan Posner

  • Tenneill Murray

  • Claudia Lugo-Candelas

  • Patricia A. Brennan

  • Christine Hockett

  • Amy Elliott

  • Lisa A. Croen

  • Monique M. Hedderson

  • John Ainsworth

  • Leonard B. Bacharier

  • Casper G. Bendixsen

  • James E. Gern

  • Diane R. Gold

  • Tina V. Hartert

  • Daniel J. Jackson

  • Christine C. Johnson

  • Christine L.M. Joseph

  • Meyer Kattan

  • Gurjit K. Khurana Hershey

  • Robert F. Lemanske, Jr.

  • Susan V. Lynch

  • Rachel L. Miller

  • George T. O’Connor

  • Carole Ober

  • Dennis Ownby

  • Katherine Rivera-Spoljaric

  • Patrick H. Ryan

  • Christine M. Seroogy

  • Anne Marie Singh

  • Robert A. Wood

  • Edward M. Zoratti

  • Rima Habre

  • Shohreh Farzan

  • Frank D. Gilliland

  • Irva Hertz-Picciotto

  • Julie B. Schweitzer

  • Janine M. LaSalle

  • Alison E. Hipwell

  • Nicole R. Bush

  • Kaja Z. LeWinn

  • Sheela Sathyanarayana

  • Frances Tylavsky

  • Kecia N. Carroll

  • Christine T. Loftus

  • Leslie D. Leve

  • Jody M. Ganiban

  • Jenae M. Neiderhiser

  • Scott T. Weiss

  • Augusto A. Litonjua

  • Cindy T. McEvoy

  • Eliot R. Spindel

  • Robert S. Tepper

  • Craig J. Newschaffer

  • Kristen Lyall

  • Heather E. Volk

  • Rebecca Landa

  • Sally Ozonoff

  • Joseph Piven

  • Heather Hazlett

  • Juhi Pandey

  • Robert Schultz

  • Steven Dager

  • Kelly Botteron

  • Daniel Messinger

  • Wendy Stone

  • Jennifer Ames

  • Thomas G. O'Connor

  • Richard K. Miller

  • Emily Oken

  • Michele R. Hacker

  • Tamarra James-Todd

  • T. Michael O'Shea

  • Rebecca C. Fry

  • Jean A. Frazier

  • Rachana Singh

  • Caitlin Rollins

  • Angela Montgomery

  • Ruben Vaidya

  • Robert M. Joseph

  • Lisa K. Washburn

  • Semsa Gogcu

  • Kelly Bear

  • Julie V. Rollins

  • Stephen R. Hooper

  • Genevieve Taylor

  • Wesley Jackson

  • Amanda Thompson

  • Julie Daniels

  • Michelle Hernandez

  • Kun Lu

  • Michael Msall

  • Madeleine Lenski

  • Rawad Obeid

  • Steven L. Pastyrnak

  • Elizabeth Jensen

  • Christina Sakai

  • Hudson Santos

  • Jean M. Kerver

  • Nigel Paneth

  • Charles J. Barone

  • Michael R. Elliott

  • Douglas M. Ruden

  • Chris Fussman

  • Amy Margolis

  • Sarah Dee Geiger

  • Andrea Aguiar

  • Karen Tabb

  • Rita Strakovsky

  • Tracey Woodruff

  • Amy Padula

  • Joseph B. Stanford

  • Angelo P. Giardino

  • Rosalind J. Wright

  • Robert O. Wright

  • Brent Collett

  • Nicole Baumann-Blackmore

  • Ronald Gangnon

  • Chris G. McKennan

  • Jo Wilson

  • Matt Altman

  • Judy L. Aschner

  • Annemarie Stroustrup

  • Stephanie L. Merhar

  • Paul E. Moore

  • Gloria S. Pryhuber

  • Mark Hudak

  • Ann Marie Reynolds Lyndaker

  • Andrea L. Lampland

  • Burton Rochelson

  • Sophia Jan

  • Matthew J. Blitz

  • Michelle W. Katzow

  • Zenobia Brown

  • Codruta Chiuzan

  • Timothy Rafael

  • Dawnette Lewis

  • Natalie Meirowitz

  • Brenda Poindexter

  • Tebeb Gebretsadik

  • Sarah Osmundson

  • Jennifer K. Straughen

  • Amy Eapen

  • Andrea Cassidy-Bushrow

  • Ganesa Wegienka

  • Alex Sitarik

  • Kim Woodcroft

  • Audrey Urquhart

  • Albert Levin

  • Tisa Johnson-Hooper

  • Brent Davidson

  • Tengfei Ma

  • Martin J. Blaser

  • Maria Gloria Dominguez-Bello

  • Daniel B. Horton

  • Manuel Jimenez

  • Todd Rosen

  • Kristy Palomares

  • Lyndsay A. Avalos

  • Kelly J . Hunt

  • Roger B. Newman

  • Michael S. Bloom

  • Mallory H. Alkis

  • James R. Roberts

  • Sunni L. Mumford

  • Heather H. Burris

  • Sara B. DeMauro

  • Lynn M. Yee

  • Aaron Hamvas

  • Antonia F. Olidipo

  • Andrew S. Haddad

  • Lisa R. Eiland

  • Nicole T. Spillane

  • Kirin N. Suri

  • Stephanie A. Fisher

  • Jeffrey A. Goldstein

  • Leena B. Mithal

  • Raye-Ann O. DeRegnier

  • Nathalie L. Maitre

  • Ruby H.N. Nguyen

  • Meghan M. JaKa

  • Abbey C. Sidebottom

  • Michael J. Paidas

  • JoNell E. Potter

  • Natale Ruby

  • Lunthita Duthely

  • Arumugam Jayakumar

  • Karen Young

  • Isabel Maldonado

  • Meghan Miller

  • Jonathan L. Slaughter

  • Sarah A. Keim

  • Courtney D. Lynch

  • Kartik K. Venkatesh

  • Kristina W. Whitworth

  • Elaine Symanski

  • Thomas F. Northrup

  • Hector Mendez-Figueroa

  • Ricardo A. Mosquera

  • Juliette C. Madan

  • Debra M. MacKenzie

  • Johnnye L. Lewis

  • Brandon J. Rennie

  • Bennett L. Leventhal

  • Young Shin Kim

  • Somer Bishop

  • Sara S. Nozadi

  • Li Luo

  • Barry M. Lester

  • Carmen J. Marsit

  • Todd Everson

  • Cynthia M. Loncar

  • Elisabeth C. McGowan

  • Stephen J. Sheinkopf

  • Brian S. Carter

  • Jennifer Check

  • Jennifer B. Helderman

  • Charles R. Neal

  • Lynne M. Smith

  • June 17, 2026

  • 0 min

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Clinical Scorecard: Impact of Maternal Exposure to Ten Classes of Priority Chemicals on Birth Outcomes in the ECHO Study

At a Glance

CategoryDetail
Condition
Key MechanismsChemicals cross the placenta, leading to fetal exposure and potential adverse outcomes (source needed).
Target Population
Care Setting

Key Highlights

  • Study involved over 60,000 US children from the ECHO Cohort (source needed).
  • Urine samples analyzed for 113 analytes from 10 chemical classes (source needed).
  • Focus on gestational age at birth and birth weight-for-gestational age (source needed).
  • Statistical analysis to adjust for various maternal factors (source needed).

Guideline-Based Recommendations

Diagnosis

    Management

    • Monitor maternal exposure to priority chemicals during pregnancy (source needed).

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        No specific treatments mentioned; focus on monitoring exposures (source needed).

        Clinical Best Practices

        • Utilize multiclass chemical panels for exposure assessment (source needed).
        • Incorporate demographic and health factors in analysis (source needed).

        Related Resources & Content

        Original Source(s)

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