Differential biomarker responses of hemolysis, inflammation, and myocardial injury after pulsed-field pulmonary vein isolation: balloon-in-basket vs. circular catheter systems - Scorecard - MDSpire

Differential biomarker responses of hemolysis, inflammation, and myocardial injury after pulsed-field pulmonary vein isolation: balloon-in-basket vs. circular catheter systems

  • By

  • Jan-Per Wenzel

  • Raed Abdessadok

  • Charlotte Eitel

  • Sorin Popescu

  • Suzanne de Waha

  • Tanja Zeller

  • Karl-Heinz Kuck

  • Roland Richard Tilz

  • Sascha Hatahet

  • May 29, 2026

  • 0 min

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Clinical Scorecard: Comparative Analysis of Biomarker Variations in Hemolysis, Inflammation, and Myocardial Damage Following Pulsed-Field Pulmonary Vein Isolation: Balloon-in-Basket Versus Circular Catheter Approaches

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPatients aged ≥18 years undergoing first-time pulmonary vein isolation (PVI) for paroxysmal or persistent atrial fibrillation.
Care Setting

Key Highlights

  • haptoglobin

Guideline-Based Recommendations

Diagnosis

    Management

    • Anticoagulation with vitamin K antagonists should be maintained at a therapeutic INR (2.0–3.0) prior to the procedure.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Both PFA systems demonstrated comparable overall biomarker responses with modest differences; monitoring should continue for at least 24 hours post-ablation.

        Clinical Best Practices

        • monitoring

        Related Resources & Content

        Original Source(s)

        Differential biomarker responses of hemolysis, inflammation, and myocardial injury after pulsed-field pulmonary vein isolation: balloon-in-basket vs. circular catheter systems

        • by Jan-Per Wenzel, Raed Abdessadok, Charlotte Eitel, Sorin Popescu, Suzanne de Waha, Tanja Zeller, Karl-Heinz Kuck, Roland Richard Tilz, Sascha Hatahet

        • May 29, 2026

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