Disseminated hepatic epithelioid hemangioendothelioma with multiorgan metastases achieving long-term stability with Pazopanib: a case report - Scorecard - MDSpire

Disseminated hepatic epithelioid hemangioendothelioma with multiorgan metastases achieving long-term stability with Pazopanib: a case report

  • By

  • Alaa Naiem Zaro

  • Salar Nael Sajadieh

  • Ansam Khaled Doudin

  • Salem K. Qupp

  • Laith Elayan

  • Ola Abu Laban

  • Marwan Qabaja

  • Amaal Alamleh

  • June 3, 2026

  • 0 min

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Clinical Scorecard: Long-term Disease Control in a Case of Disseminated Hepatic Epithelioid Hemangioendothelioma with Multiorgan Metastases Treated with Pazopanib

At a Glance

CategoryDetail
Condition
Key MechanismsMalignant vascular neoplasm arising from endothelial cells, often misdiagnosed as metastasis from other tumors. Include recent findings on etiology.
Target Population
Care Setting

Key Highlights

  • treatment_insights

Guideline-Based Recommendations

Diagnosis

    Management

    • Consider radical surgery or liver transplantation, though risks of recurrence exist.
    • Explore targeted therapies and clinical trials as potential options.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        A 28-year-old male with multifocal HEHE and metastatic disease.

        Pazopanib was initiated as part of the biological treatment plan.

        Clinical Best Practices

        • Consider EHE in differential diagnoses of vascular tumors.
        • Utilize comprehensive imaging for staging and monitoring.

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        Original Source(s)

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