Research and development of novel embolization materials and study on their feasibility of preventing T2EL after EVAR abdominal aortic aneurysm - Scorecard - MDSpire
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Research and development of novel embolization materials and study on their feasibility of preventing T2EL after EVAR abdominal aortic aneurysm
Clinical Scorecard: Development of Innovative Embolization Materials and Assessment of Their Efficacy in Preventing Type II Endoleak After Endovascular Aneurysm Repair for Abdominal Aortic Aneurysm
At a Glance
Category
Detail
Condition
Type II Endoleak (T2EL) after Endovascular Aneurysm Repair (EVAR) for Abdominal Aortic Aneurysm (AAA)
Key Mechanisms
Thrombin-Coated Controllable Coil (TCC) enhances thrombosis and prevents T2EL.
Target Population
Patients undergoing EVAR for AAA, particularly those at risk for T2EL.
Care Setting
Endovascular surgical procedures.
Key Highlights
TCC significantly shortened coagulation time compared to IDC and control groups.
TCC achieved complete thrombosis within the aneurysm without complications.
In vitro, TCC promoted apoptosis of vascular smooth muscle cells (VSMCs) and inhibited their proliferation.
