Case Report: Indocyanine green fluorescence imaging in complex focal nodular hyperplasia resection: report of two cases - Scorecard - MDSpire

Case Report: Indocyanine green fluorescence imaging in complex focal nodular hyperplasia resection: report of two cases

  • By

  • Fangkai Du

  • Xie Song

  • Wentao Wang

  • Huizhong Shi

  • Zhengjian Wang

  • Chaoqun Ma

  • Qingqiang Ni

  • Shunzhen Zheng

  • Hong Chang

  • June 15, 2026

  • 0 min

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Clinical Scorecard: Clinical Insights: Utilizing Indocyanine Green Fluorescence Imaging for Resection of Complex Focal Nodular Hyperplasia - A Report on Two Cases

At a Glance

CategoryDetail
Condition
Key MechanismsIndocyanine green (ICG) fluorescence imaging combined with intraoperative ultrasonography (IOUS) for lesion localization and margin assessment.
Target Population
Care Setting

Key Highlights

  • ICG fluorescence imaging aids in precise lesion delineation during surgery.
  • Successful wedge excision achieved with negative surgical margins in both cases.
  • Estimated blood loss was minimal (50-20 mL).
  • Incidental hyperfluorescent foci observed; clinical significance remains uncertain.
  • Further studies needed to assess reproducibility and clinical value.

Guideline-Based Recommendations

Diagnosis

  • Consider resection for atypical imaging features or persistent diagnostic uncertainty.

Management

  • Laparoscopic parenchyma-sparing excision may be indicated in selected cases.

Monitoring & Follow-up

  • Postoperative follow-up imaging to assess for residual or recurrent lesions.

Risks

  • Potential for vascular injury in lesions located near major vessels.

Patient & Prescribing Data

Two women aged 50 and 51 with incidental liver lesions.

Preoperative ICG administration (0.5 mg/kg) enhances intraoperative navigation.

Clinical Best Practices

  • Utilize dual-modality navigation (ICG and IOUS) for complex FNH resections.
  • Ensure thorough preoperative imaging to assess lesion characteristics.
  • Multidisciplinary team review for cases with diagnostic uncertainty.

Related Resources & Content

Original Source(s)

Case Report: Indocyanine green fluorescence imaging in complex focal nodular hyperplasia resection: report of two cases

  • by Fangkai Du, Xie Song, Wentao Wang, Huizhong Shi, Zhengjian Wang, Chaoqun Ma, Qingqiang Ni, Shunzhen Zheng, Hong Chang

  • June 15, 2026

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