Smoldering Waldenström macroglobulinemia coexisting with myelodysplastic syndrome: a rare case report and literature review - Scorecard - MDSpire

Smoldering Waldenström macroglobulinemia coexisting with myelodysplastic syndrome: a rare case report and literature review

  • By

  • Huanyuan Wang

  • Shuai Tan

  • Yumeng Li

  • Wanling Sun

  • May 25, 2026

  • 0 min

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Clinical Scorecard: Coexisting Smoldering Waldenström Macroglobulinemia and Myelodysplastic Syndrome: An Uncommon Case Study and Review of Existing Literature

At a Glance

CategoryDetail
Condition
Key MechanismsCharacterized by monoclonal IgM production, dysplastic changes in bone marrow, and associated cytopenias such as anemia, neutropenia, and thrombocytopenia.
Target Population
Care Setting

Key Highlights

  • Clarify the role of FLT3-ITD mutation in disease progression and treatment response.

Guideline-Based Recommendations

Diagnosis

    Management

    • Consider additional treatment options such as clinical trials for MDS/AML.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Detail the patient's treatment response and any side effects experienced during therapy.

        Clinical Best Practices

        • monitoring

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          Original Source(s)

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